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Mission statement
The division Sanquin Diagnostic Services (former CLB Diagnostic Services) advises and conducts blood testing in the field of transfusion medicine and immunology. Sanquin Diagnostic Services works according to the highest levels of quality with dedicated professionals and scientific support.

Certified by the Dutch Accreditation Council

Scope of the accreditation

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Biologicals

Over the last few years various biologicals (therapeutic proteins) have been brought on the market, including the monoclonal antibodies against TNFα (infliximab, adalimumab, etanercept) and CD20 (rituximab). With the 2008 EMEA- and FDA-guidelines now in effect, assessment of antibody responses against biologicals has become a matter of great interest. For many years Sanquin and the Jan van Breemen Institute have been studying the clinical relevance of those antibody responses. It appears that biologicals elicit an antibody response in a substantial number of patients, resulting in the loss of efficacy of treatment. For quite some time, Sanquin has been carrying out immunogenicity tests for rheumatologists, dermatologists and gastroenterologists on a routine basis, using a standard assay format. By closely monitoring drug levels and antibody formation, it has now become possible to adjust treatment to each individual patient. Click here for more information.


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Custodianship of the WHO Biological Standards
Per January 2007 Sanquin discontinued the custodianship of the WHO Biological Standards. See more.


Last Modified: 11 April 2010 11:44
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